[Effect of social support from husband on the control of risk factors for metabolic syndrome]

Metabolic syndrome, a combination of obesity, impaired glucose tolerance, hypertension, low high-density cholesterol, and increased triglyceride levels, is now one of the most common diseases throughout the world. This study aimed to determine the effect of the husbands, social support on the control of risk factors for metabolic syndrome in women. In this clinical trial, 182 women with metabolic syndrome were systematic randomly divided into two, the experimental and the control groups. A self designed valid and reliable questionnaire on "perceived social support from husband" and a "24-hour dietary recall" questionnaire were used. Also, a data sheet used to record data on waist circumference, systolic [SBP] and diastolic blood pressure, [DBP] TG, HDL and FBS. After data collection, educational interventions were used, and 3 months after intervention, post-test results were collected. Mean scores of husband social support in the experimental group was significantly higher than the control group. Also, after the intervention, significant decrease in macronutrient [fat and carbohydrate] intake was seen in the experimental group, compared to controls. Moreover, mean waist circumference [4.2 cm], triglycerides concentration [54.15 mg/dL, fasting blood sugar, 61.13 mg/dL;] SBP 7.42 mmHg and DBP 9.55 mmHg were decreased, and mean HDL increased to 5.87 mg/dL; all changes were significantly greater than the control group. Improvement in perceived social support from husband could contribute to following a healthy diet and consequently, may reduce the risk factors of metabolic syndrome in women

[Relationship of perceived social support with receiving macronutrients in women with metabolic syndrome; a cross sectional study using path analysis study]

Metabolic syndrome, defined as a combination of certain series of problems metabolic disorders, is a prevalent disease, significantly more common among women. One way to prevent this disease is to control the diet, which is affected by various intrapersonal, interpersonal and social factors. This research of aims at determining the association between patient consumption of macronutrients influencing metabolic syndrome and the perceived social support of their husbands. This is a cross sectional study, conducted using the correlation method on 329 patients, referred to medical centers of the oil industry. Information on perceived social support was measured by a researcher made, 24 hour questionnaire, with confirmed reliability and validity, to asserss nutritional behavior for three days. Data was analyzed by N4, SPSS and AMOS for the model constructed, using the least extended squares. The averages of daily intakes of energy, protein, carbohydrate and fat were 2512.37, 70.95, 420 and 61.61 grams respectively. The average of perceived social support was 65.48. Correlation coefficient showed a significantly inverse relationship between perceived social support and macronutrients received in these women. The hight correlation between social support and fat was observed [beta=-0.606]. Intakes of energy, fat, carbohydrate and protein were higher than RDA and average levels of perceived social support, showing that social support is an effective framework to recognize and predict commitment level of nutritional self care behavior among patients suffering from metabolic syndrome

[Eosinophilic gastroenteritis with clinical manifestations of small bowel obstruction: a case report]

Eosinophilic gastroenteritis is a rare disease with eosinophilic infiltration of the wall of the gastrointestinal tract, especially in stomach and small bowel. The etiology of the disease is unknown. A 61 year man was admitted because of epigastric pain for 10 days with burning quality with an increase after each meal. Laboratory tests showed mild leukocytosis with 5% eosinophilia, mildly elevated ESR and CRP and serum IgE at upper normal limit. Increased mucosal thickness was shown in posterior gastric wall and the descending part of duodenum seemed narrow with thick irregular wall. CT scan and esophago-gastro-duedenoscopy revealed gastric distention and erythema in D1 region with luminal narrowing. Pathology report from D1, showed inflammatory infiltration with eosinophilia in lamina propria. The patient was treated with oral prednisolone. All complaints and manifestations disappeared soon after treatment and the radiologic studies showed normal image

expression profile of indolamine 2,3-dioxygenase in murine endometrium during estrous cycle

Activation of Indolamine 2,3-dioxygenase [IDO], an enzyme responsible for tryptophan catabolism, has been reported to be a necessary requirement to achieve immunological tolerance against the fetus and protection against intracellular and extracellular pathogens. The objective of this study was to evaluate the expression of IDO gene in murine endometrium and its expression rate in different phases of estrous cycle. Noticing the role of this enzyme especially in the survival of a semi-antigenic embryo, the results of this study may be used as a basis for practical studies on the immunologic bases of recurrent abortions. In this experimental study, we studied the expression of IDO in the female BALB/c mice endometrium during four stages of estrous cycle. The phases of estrous cycle were determined by examining vaginal cytology .At each phase, endometrium was pealed away and the relative expression of IDO mRNA was detected by semi-quantitative RT-PCR using specific primers to IDO and mGAPDH as a housekeeping gene. The specificity of reaction was confirmed by enzymatic digestion of amplicon which yielded to 138bp and 259bp fragments. Our results showed, for the first time, that IDO is expressed in the endometrium of cycling mice during all stages of estrous cycle. The expression of IDO was highest at estrus and lowest at diestrus [p<.001]. Expression of IDO in endometrium during all phases of estrous cycle reveals that this enzyme as an effective arm of innate immune system may serve a role in protecting the female reproductive tract against ascending infections. Also regarding the fact that, mating only occurs at estrus phase, the high expression of IDO in this phase, may act as the main mechanism in inducing immunological tolerance to the fetus